Prediction of gestational diabetes mellitus in the first trimester: is it possible?

Objective: The aim of this study is to identify the first trimester markers that may be associated with gestational diabetes mellitus (GDM) and evaluate whether those might used for prediction or not. Methods: Pregnant women between 11 14 weeks gestation applying university hospital August 2018 March 2019 were included in study. Body mass index calculation blood tests including complete count, TSH, T3, T4, HbA1c, uric acid, CRP, procalcitonin, PAPP-A b-hCG levels done during assessment followed by 50 grams glucose challenge test 24 28 each woman. Patients positive results further evaluated a 3-hour, 100-g OGTT. According diagnostic results, relationship biochemical trimester, BMI GDM was statistically analyzed. Results: A hundred eighty-two pregnant participated Fifty-four had (GCT) while 128 negative results. GCT underwent OGTT and, diagnosed GDM, 158 considered healthy according There no significant difference non-GDM groups terms age, height, b-hCG-mom, PAPP-A, PAPP-A-mom, acid procalcitonin (p>0.05). mean body weight, HbA1c higher lower group compared group, these findings (p<0.001). Conclusion: use seems have significance. need extensive, randomized studies universal criteria.